SLC25A42

Across TCGA patient cohorts, SLC25A42 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A42-associated genes across cancer lineages are Caspase-7-cleavedD198, Bak, and 4E-BP1. Each is linked with SLC25A42 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A42-to-partner and partner-to-SLC25A42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by SLC25A42-low versus SLC25A42-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A42→partner) and Y-score (partner→SLC25A42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.843	+3.479	.001	.002	3	3
UCEC	Bak →	+0.296	+2.584	.006	.010	3	2
UCEC	4E-BP1 →	+0.360	+2.199	.002	.033	3	2
UCEC	eEF2 →	+0.362	+2.115	.020	.019	3	1
UCEC	EGFR_pY1068 →	-0.378	-3.584	<.001	.002	3	1
UCEC	FASN →	+0.434	+3.000	.011	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Caspase-7-cleavedD198 by SLC25A42 expression — UCEC

Explore this box plot interactively →