SLC25A41

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A41 mutation is significantly associated with the RNA expression of many other genes, with 1,284 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A41-associated genes across cancer lineages are TAF9, RPS29P32, and NOP10. Each is linked with SLC25A41 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A41-to-partner and partner-to-SLC25A41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by SLC25A41-low versus SLC25A41-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A41→partner) and Y-score (partner→SLC25A41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTAF9 →+0.714+3.000<.001.00132
UCECRPS29P32 →+0.414+2.221<.001.00832
UCECNOP10 →+0.546+3.757<.001<.00132
UCECGLRX5 →+0.380+2.617.008.00532
UCECRPL23AP82 →+0.443+3.010<.001<.00132
UCECCDCA2 →+0.807+3.716.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,284 associations by consensus.

TAF9 by SLC25A41 expression — UCEC

Box plot of TAF9 in SLC25A41-low vs SLC25A41-high samples in UCEC.

Explore this box plot interactively →

Exploration