SLC25A41

Across TCGA cell cohorts, SLC25A41 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A41-associated genes across cancer lineages are CRYBB1, OR6V1, and CA6. Each is linked with SLC25A41 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A41-to-partner and partner-to-SLC25A41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB1 grouped by SLC25A41-low versus SLC25A41-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A41→partner) and Y-score (partner→SLC25A41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CRYBB1 →	+0.019	+5.000	<.001	.006	3	1
PANCREAS	OR6V1 →	+0.022	+5.000	<.001	.006	3	1
BLOOD_Leukemia	CA6 →	+0.592	+3.066	.005	.006	3	1
BLOOD_Leukemia	KCNH1 →	+0.257	+3.632	<.001	.003	3	1
BLOOD_Leukemia	CDR1 →	+0.058	+3.475	<.001	.001	3	1
BLOOD_Leukemia	MTRNR2L5 →	+0.012	+3.984	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

CRYBB1 by SLC25A41 expression — PANCREAS

Explore this box plot interactively →