SLC25A4

Across TCGA patient cohorts, SLC25A4 mutation is significantly associated with the RNA expression of many other genes, with 1,730 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A4-associated genes across cancer lineages are RNA5SP143, MTND5P41, and DOC2B. Each is linked with SLC25A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A4-to-partner and partner-to-SLC25A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP143 grouped by SLC25A4-low versus SLC25A4-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A4→partner) and Y-score (partner→SLC25A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP143 →	+0.255	+7.731	<.001	.009	3	1
BRCA	MTND5P41 →	+0.283	+7.731	<.001	.009	3	1
UCEC	DOC2B →	-1.355	-3.584	<.001	.002	3	1
UCEC	CHASERR →	+0.558	+3.202	.008	.009	3	1
UCEC	TAF9 →	+0.584	+3.584	<.001	.002	3	1
UCEC	MIR7702 →	+0.229	+4.253	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,730 associations by consensus.

RNA5SP143 by SLC25A4 expression — BRCA

Explore this box plot interactively →