SLC25A3P2

Across TCGA pan-cancer cohorts, SLC25A3P2 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated SLC25A3P2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC25A3P2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SLC25A3P2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, STAD, and ACC are the cancer types where SLC25A3P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.726	0.588	.003	56	view →
STAD	DFS	Quartile	IV	0.080	0.816	.001	33	view →
ACC	OS	Quartile	II,III,IV	0.424	1.000	.014	22	view →
LIHC	OS	Median	II,III,IV	0.590	0.762	.020	20	view →
SKCM	OS	Tertile	III,IV	0.539	0.303	.005	18	view →
COAD	DFS	Tertile	All	0.839	0.734	.009	15	view →
BRCA	DFS	Tertile	All	0.341	0.554	.021	9	view →
LUSC	DFS	Median	All	0.788	0.712	.015	9	view →
READ	OS	Quartile	II,III,IV	0.741	1.000	.004	9	view →
THYM	OS	Median	All	0.983	0.753	.012	8	view →
ESCA	OS	Quartile	III,IV	0.715	0.387	.032	6	view →
LUAD	DFS	Quartile	III,IV	0.827	0.431	.020	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

SLC25A3P2–HNSC (OS)

Open the HNSC breakdown →