SLC25A38

Across TCGA patient cohorts, SLC25A38 mutation is significantly associated with the RNA expression of many other genes, with 1,401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A38-associated genes across cancer lineages are NME1P1, RNU6-1246P, and RN7SL719P. Each is linked with SLC25A38 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A38-to-partner and partner-to-SLC25A38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NME1P1 grouped by SLC25A38-low versus SLC25A38-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A38→partner) and Y-score (partner→SLC25A38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NME1P1 →	+0.104	+5.485	<.001	.001	3	2
SKCM	RNU6-1246P →	+0.227	+5.810	<.001	<.001	3	2
UCEC	RN7SL719P →	+0.068	+4.601	<.001	.003	3	1
UCEC	FCGBP →	-1.603	-3.443	<.001	.005	3	1
UCEC	MLECP1 →	+0.059	+4.056	.006	<.001	3	1
SKCM	CTBP2P9 →	+0.076	+5.080	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,401 associations by consensus.

NME1P1 by SLC25A38 expression — SKCM

Explore this box plot interactively →