SLC25A38

Across TCGA patient cohorts, SLC25A38 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A38-associated genes across cancer lineages are Annexin-1, ATM, and Bim. Each is linked with SLC25A38 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A38-to-partner and partner-to-SLC25A38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by SLC25A38-low versus SLC25A38-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A38→partner) and Y-score (partner→SLC25A38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.952	+3.321	<.001	.010	3	1
UCEC	ATM →	-0.467	-3.321	.049	.010	3	1
UCEC	Bim →	-0.277	-3.321	.044	.010	3	1
UCEC	P-Cadherin →	-0.198	-3.308	.008	.010	1	1
UCEC	Rad50 →	-0.338	-3.321	.007	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Annexin-1 by SLC25A38 expression — UCEC

Explore this box plot interactively →