SLC25A36

Across TCGA pan-cancer cohorts, SLC25A36 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC25A36 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC25A36 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A36 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where SLC25A36 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.283	0.873	<.001	42	view →
LUAD	DFS	Median	III,IV	1.000	0.320	.026	7	view →
LSCC	OS	Tertile	All	1.000	0.915	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC25A36–CCRCC (DFS)

Open the CCRCC breakdown →