SLC25A36

Across TCGA pan-cancer cohorts, SLC25A36 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SLC25A36’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where SLC25A36 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types SLC25A36 is over-expressed in tumor, although a few such as CCRCC and PDAC show the opposite, repressed pattern.

CCRCC, PDAC, and HNSC are the cancer types where SLC25A36 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A36 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	Female	All	−0.503	<.001	8	view →
PDAC	All	All	−0.689	.001	5	view →
HNSC	All	All	+0.483	.038	4	view →
LUAD	Female	All	+0.285	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SLC25A36–CCRCC

Open the CCRCC breakdown →