SLC25A36

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A36 mutation is significantly associated with the RNA expression of many other genes, with 519 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A36-associated genes across cancer lineages are RNU6-1309P, CFAP97P1, and MIR7843. Each is linked with SLC25A36 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A36-to-partner and partner-to-SLC25A36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1309P grouped by SLC25A36-low versus SLC25A36-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A36→partner) and Y-score (partner→SLC25A36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRNU6-1309P →+0.901+4.372<.001.00732
LUADCFAP97P1 →+0.200+5.000.002.00232
LUADMIR7843 →+0.486+5.864<.001<.00132
BRCARNU6-860P →+0.303+8.055<.001.00732
SKCMMIR422A →+0.279+4.594.003.00832
SKCMPDK1P2 →+0.030+5.080<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 519 associations by consensus.

RNU6-1309P by SLC25A36 expression — LUAD

Box plot of RNU6-1309P in SLC25A36-low vs SLC25A36-high samples in LUAD.

Explore this box plot interactively →

Exploration