SLC25A36

Across TCGA patient cohorts, SLC25A36 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A36-associated genes across cancer lineages are Notch1, Src, and EGFR_pY1068. Each is linked with SLC25A36 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A36-to-partner and partner-to-SLC25A36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by SLC25A36-low versus SLC25A36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A36→partner) and Y-score (partner→SLC25A36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.200	+3.169	.009	.020	3	1
UCEC	Src →	+0.276	+3.169	.014	.020	3	1
UCEC	EGFR_pY1068 →	-0.328	-3.169	.017	.020	1	1
UCEC	MEK1 →	+0.570	+3.169	.004	.020	1	1
UCEC	mTOR_pS2448 →	-0.209	-3.169	.010	.020	1	1
UCEC	p38-MAPK_pT180_Y182 →	-0.763	-3.156	.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Notch1 by SLC25A36 expression — UCEC

Explore this box plot interactively →