SLC25A36

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A36 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A36-associated genes across cancer lineages are SPHKAP and DBX2. Each is linked with SLC25A36 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A36-to-partner and partner-to-SLC25A36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPHKAP grouped by SLC25A36-low versus SLC25A36-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A36→partner) and Y-score (partner→SLC25A36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESPHKAP →+0.006+5.415.007.00431
LARGE_INTESTINEDBX2 →+0.023+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SPHKAP by SLC25A36 expression — LARGE_INTESTINE

Box plot of SPHKAP in SLC25A36-low vs SLC25A36-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration