SLC25A35

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A35 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A35-associated genes across cancer lineages are Chondrocytes, MEP, and CD4+ Tem. Each is linked with SLC25A35 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A35-to-partner and partner-to-SLC25A35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondrocytes grouped by SLC25A35-low versus SLC25A35-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A35→partner) and Y-score (partner→SLC25A35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMChondrocytes →+0.025+3.923<.001.02032
UCECMEP →+0.035+2.711.005.00332
CESCCD4+ Tem →+0.001+5.589.005.02731
UCECPlasma cells →-0.019-1.957.045.03231
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Chondrocytes by SLC25A35 expression — SKCM

Box plot of Chondrocytes in SLC25A35-low vs SLC25A35-high samples in SKCM.

Explore this box plot interactively →

Exploration