SLC25A33

Across TCGA pan-cancer cohorts, SLC25A33 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC25A33 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SLC25A33 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC25A33 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, LUAD, and GBM are the cancer types where SLC25A33 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.975	0.632	.025	17	view →
LUAD	OS	Tertile	All	0.893	0.577	.043	4	view →
GBM	DFS	Quartile	All	0.531	0.282	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC25A33–LSCC (OS)

Open the LSCC breakdown →