SLC25A30

Across TCGA patient cohorts, SLC25A30 mutation is significantly associated with the RNA expression of many other genes, with 3,448 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A30-associated genes across cancer lineages are MAP6D1, CDCA2, and NDUFA6. Each is linked with SLC25A30 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A30-to-partner and partner-to-SLC25A30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAP6D1 grouped by SLC25A30-low versus SLC25A30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A30→partner) and Y-score (partner→SLC25A30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP6D1 →	+0.486	+2.124	.001	<.001	3	2
UCEC	CDCA2 →	+0.953	+2.459	<.001	<.001	3	2
UCEC	NDUFA6 →	+0.437	+2.550	<.001	<.001	3	2
UCEC	MAPK12 →	+0.817	+2.095	<.001	.003	3	2
UCEC	MAK16 →	+0.517	+2.938	<.001	<.001	3	2
UCEC	GPATCH3 →	+0.325	+2.930	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,448 associations by consensus.

MAP6D1 by SLC25A30 expression — UCEC

Explore this box plot interactively →