SLC25A30

Across TCGA patient cohorts, SLC25A30 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A30-associated genes across cancer lineages are C-Raf, eIF4E, and PDCD4. Each is linked with SLC25A30 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A30-to-partner and partner-to-SLC25A30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C-Raf grouped by SLC25A30-low versus SLC25A30-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A30→partner) and Y-score (partner→SLC25A30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C-Raf →	+0.209	+2.815	.009	.036	3	3
UCEC	eIF4E →	+0.203	+2.584	.011	.001	3	2
UCEC	PDCD4 →	-0.471	-1.990	.009	.030	3	2
UCEC	Cyclin-B1 →	+0.689	+3.807	.001	<.001	3	2
COAD	ASNS →	+1.048	+2.815	<.001	.036	3	2
UCEC	Fibronectin →	-0.254	-1.690	.045	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

C-Raf by SLC25A30 expression — COAD

Explore this box plot interactively →