SLC25A3

Across TCGA patient cohorts, SLC25A3 protein abundance is significantly associated with the RNA expression of many other genes, with 20,390 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC25A3-associated genes across cancer lineages are ETS1, RASSF2, and NCF2. Each is linked with SLC25A3 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC25A3-to-partner and partner-to-SLC25A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A3 versus ETS1 in OV, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A3→partner) and Y-score (partner→SLC25A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ETS1 →	-0.804	-0.437	<.001	<.001	3	6
LSCC	RASSF2 →	-0.902	-0.385	<.001	<.001	3	6
COAD	NCF2 →	-0.935	-0.278	<.001	<.001	3	6
OV	GIMAP6 →	-0.839	-0.444	<.001	<.001	3	6
OV	CLEC7A →	-0.685	-0.386	<.001	<.001	3	6
OV	COX6A1 →	+0.826	+0.389	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,390 associations by consensus.

SLC25A3 vs ETS1 — OV

Explore this scatter interactively →