SLC25A28

Across TCGA pan-cancer cohorts, SLC25A28 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC25A28 data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SLC25A28 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A28 expression acts as an unfavorable survival marker.

SKCM, UCS, and KIRP are the cancer types where SLC25A28 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	III,IV	0.054	0.616	<.001	10	view →
UCS	OS	Median	All	0.153	0.687	.019	6	view →
KIRP	OS	Median	All	0.608	0.903	.029	6	view →
BLCA	OS	Median	IV	0.183	0.598	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC25A28–SKCM (DFS)

Open the SKCM breakdown →