SLC25A28

Across TCGA patient cohorts, SLC25A28 mutation is significantly associated with the RNA expression of many other genes, with 2,769 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A28-associated genes across cancer lineages are MIR3180-4, SNORD114-18, and IGHD3-22. Each is linked with SLC25A28 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A28-to-partner and partner-to-SLC25A28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3180-4 grouped by SLC25A28-low versus SLC25A28-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A28→partner) and Y-score (partner→SLC25A28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR3180-4 →	+0.258	+7.640	<.001	.009	3	3
UCEC	SNORD114-18 →	+0.372	+2.814	<.001	.001	3	2
UCEC	IGHD3-22 →	+1.602	+1.925	<.001	.005	3	2
UCEC	MIR132 →	+0.286	+2.864	<.001	.003	3	2
BLCA	WARS2P1 →	+0.084	+7.640	<.001	.009	3	2
COAD	OR5D3P →	+0.066	+5.332	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,769 associations by consensus.

MIR3180-4 by SLC25A28 expression — BLCA

Explore this box plot interactively →