SLC25A28

Across TCGA cell cohorts, SLC25A28 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,637 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A28-associated GO terms across cancer lineages are Negative regulation of telomere maintenance, Protein deacetylation, and Excitatory postsynaptic potential. Each is linked with SLC25A28 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC25A28-to-partner and partner-to-SLC25A28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere maintenance grouped by SLC25A28-low versus SLC25A28-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A28→partner) and Y-score (partner→SLC25A28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of telomere maintenance →	+0.081	+0.660	<.001	.005	3	9
OESOPHAGUS	Protein deacetylation →	+0.139	+0.857	<.001	.007	3	8
SOFT_TISSUE	Excitatory postsynaptic potential →	-0.070	-0.692	.008	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.097	+0.790	<.001	.009	3	8
LUNG_SCLC	Positive regulation of maintenance of sister chromatid cohesion →	+0.074	+0.471	.004	.001	3	8
LUNG_SCLC	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.074	+0.471	.004	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,637 associations by consensus.

Negative regulation of telomere maintenance by SLC25A28 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →