SLC25A26

Across TCGA pan-cancer cohorts, SLC25A26 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC25A26 data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC25A26 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC25A26 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where SLC25A26 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	III,IV	0.804	0.470	.008	36	view →
PDAC	DFS	Median	All	0.683	0.996	.003	26	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	15	view →
OV	DFS	Median	All	0.942	0.608	.041	4	view →
LSCC	DFS	Quartile	All	0.305	0.844	.022	4	view →
GBM	DFS	Median	All	0.783	0.704	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC25A26–HNSC (DFS)

Open the HNSC breakdown →