SLC25A26

Across TCGA patient cohorts, SLC25A26 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A26-associated genes across cancer lineages are Ku80, Myosin-IIa_pS1943, and Shc_pY317. Each is linked with SLC25A26 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A26-to-partner and partner-to-SLC25A26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by SLC25A26-low versus SLC25A26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A26→partner) and Y-score (partner→SLC25A26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.263	+2.183	.033	.035	3	1
UCEC	Myosin-IIa_pS1943 →	+0.219	+2.183	.043	.035	3	1
UCEC	Shc_pY317 →	-0.270	-3.000	<.001	.036	3	1
UCEC	VEGFR2 →	+0.321	+2.183	.039	.035	3	1
UCEC	VHL →	-1.465	-3.321	<.001	.010	3	1
UCEC	Caspase-8 →	-0.363	-2.973	.005	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Ku80 by SLC25A26 expression — UCEC

Explore this box plot interactively →