SLC25A24

Across TCGA pan-cancer cohorts, SLC25A24 mass-spec protein is linked to patient survival in 9 of 34 cancer types, making it a survival-associated SLC25A24 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SLC25A24 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC25A24 expression acts as an unfavorable survival marker, although some lineages such as COAD and OV show a favorable association.

COAD, UCEC, and LSCC are the cancer types where SLC25A24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	All	1.000	0.885	.039	6	view →
UCEC	DFS	Quartile	II,III,IV	0.514	1.000	.025	6	view →
LSCC	DFS	Median	All	0.889	0.971	.008	6	view →
OV	DFS	Median	All	1.000	0.835	.037	4	view →
CCRCC	DFS	Tertile	All	0.605	0.863	.030	2	view →
HNSC	DFS	Median	All	0.922	0.980	.033	2	view →
LUAD	OS	Median	II,III,IV	0.844	0.948	.046	2	view →
GBM	DFS	Tertile	All	0.288	0.452	.049	2	view →
PDAC	DFS	Tertile	All	0.694	0.824	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

SLC25A24–COAD (DFS)

Open the COAD breakdown →