SLC25A24

Across TCGA patient cohorts, SLC25A24 mutation is significantly associated with the RNA expression of many other genes, with 1,757 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A24-associated genes across cancer lineages are RNU6-347P, ATP6V1D, and MRPL19. Each is linked with SLC25A24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A24-to-partner and partner-to-SLC25A24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-347P grouped by SLC25A24-low versus SLC25A24-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A24→partner) and Y-score (partner→SLC25A24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-347P →	+0.162	+5.643	<.001	<.001	3	2
UCEC	ATP6V1D →	+0.398	+1.914	<.001	.001	3	2
UCEC	MRPL19 →	+0.414	+2.008	.005	.001	3	2
UCEC	KIAA1191 →	+0.380	+2.095	.001	.003	3	2
UCEC	PARP2 →	+0.348	+2.296	.006	<.001	3	2
UCEC	ZCCHC9 →	+0.424	+2.818	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,757 associations by consensus.

RNU6-347P by SLC25A24 expression — SKCM

Explore this box plot interactively →