SLC25A24

Across TCGA patient cohorts, SLC25A24 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A24-associated genes across cancer lineages are FOXO3a, EGFR_pY1068, and A-Raf_pS299. Each is linked with SLC25A24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A24-to-partner and partner-to-SLC25A24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXO3a grouped by SLC25A24-low versus SLC25A24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A24→partner) and Y-score (partner→SLC25A24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	-0.073	-1.555	.046	.034	3	2
UCEC	EGFR_pY1068 →	-0.287	-2.906	.001	.001	3	1
UCEC	A-Raf_pS299 →	-0.156	-3.906	<.001	<.001	3	1
UCEC	ERK2 →	+0.225	+1.925	.001	.005	2	2
UCEC	HER3_pY1289 →	+0.061	+1.874	.047	.049	3	1
UCEC	INPP4B →	-0.284	-2.584	.014	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

FOXO3a by SLC25A24 expression — UCEC

Explore this box plot interactively →