SLC25A24

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A24 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A24-associated genes across cancer lineages are IFNA17, TBC1D21, and OR5B2. Each is linked with SLC25A24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A24-to-partner and partner-to-SLC25A24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA17 grouped by SLC25A24-low versus SLC25A24-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A24→partner) and Y-score (partner→SLC25A24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYIFNA17 →+0.020+5.807<.001.00131
LARGE_INTESTINETBC1D21 →+0.012+4.437<.001.00431
LARGE_INTESTINEOR5B2 →+0.015+3.684.003.00631
BLOOD_LeukemiaCCNP →+0.215+3.498.001.00431
BLOOD_LeukemiaCFHR3 →+0.599+2.793<.001.00331
BLOOD_LeukemiaCA14 →+0.421+3.199<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

IFNA17 by SLC25A24 expression — OVARY

Box plot of IFNA17 in SLC25A24-low vs SLC25A24-high samples in OVARY.

Explore this box plot interactively →

Exploration