SLC25A21

Across TCGA patient cohorts, SLC25A21 protein abundance is significantly associated with the RNA expression of many other genes, with 7,065 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC25A21-associated genes across cancer lineages are FKBP3, DNAAF2, and GLRX5. Each is linked with SLC25A21 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A21-to-partner and partner-to-SLC25A21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A21 versus FKBP3 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A21→partner) and Y-score (partner→SLC25A21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FKBP3 →	+0.812	+1.011	<.001	.004	3	3
LSCC	DNAAF2 →	+0.598	+0.798	<.001	<.001	3	3
LSCC	GLRX5 →	+1.004	+1.239	<.001	<.001	3	3
LSCC	L2HGDH →	+0.719	+0.771	<.001	<.001	3	3
LUAD	MIPOL1 →	+1.245	+1.583	<.001	<.001	3	3
LSCC	CASP4 →	-0.536	-0.881	.008	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,065 associations by consensus.

SLC25A21 vs FKBP3 — LSCC

Explore this scatter interactively →