SLC25A21

Across TCGA patient cohorts, SLC25A21 mutation is significantly associated with the RNA expression of many other genes, with 2,266 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A21-associated genes across cancer lineages are NOL12, ATP5MC1, and MED27. Each is linked with SLC25A21 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A21-to-partner and partner-to-SLC25A21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOL12 grouped by SLC25A21-low versus SLC25A21-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A21→partner) and Y-score (partner→SLC25A21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOL12 →	+0.379	+3.338	.002	.005	3	2
UCEC	ATP5MC1 →	+0.500	+3.625	.003	.001	3	2
UCEC	MED27 →	+0.477	+2.871	.001	.001	3	2
UCEC	BAP1 →	+0.436	+3.467	.001	.002	3	2
UCEC	RCCD1 →	+0.590	+3.928	<.001	<.001	3	2
UCEC	UBXN6 →	+0.483	+2.828	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,266 associations by consensus.

NOL12 by SLC25A21 expression — UCEC

Explore this box plot interactively →