Across TCGA cell cohorts, SLC25A21 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,021 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A21-associated GO terms across cancer lineages are Alpha-ketoglutarate transport, Chromosomal 5-methylcytosine DNA demethylation pathway, and Positive regulation of translation. Each is linked with SLC25A21 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC25A21-to-partner and partner-to-SLC25A21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A21→partner) and Y-score (partner→SLC25A21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Alpha-ketoglutarate transport →	-0.469	-0.934	<.001	<.001	3	12
BONE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.150	+1.436	.002	.004	3	10
OESOPHAGUS	Positive regulation of translation →	+0.079	+1.325	.001	.001	3	9
BONE	Macromolecule methylation →	+0.066	+1.191	<.001	.002	3	8
BONE	Positive regulation of DNA repair →	+0.078	+1.515	<.001	<.001	3	8
CNS	Mitochondrial gene expression →	+0.065	+1.049	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,021 associations by consensus.

Exploration

SLC25A21 survival (RNA) · tumor vs normal (RNA) · all SLC25A21 data types