Across TCGA cell cohorts, SLC25A21 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC25A21-associated genes across cancer lineages are KRT2, SEC14L3, and DEFA6. Each is linked with SLC25A21 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A21-to-partner and partner-to-SLC25A21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A21→partner) and Y-score (partner→SLC25A21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRT2 →	+0.308	+4.350	<.001	.005	3	1
SKIN	SEC14L3 →	+0.013	+4.977	<.001	.007	3	1
SKIN	DEFA6 →	+0.264	+4.977	<.001	.007	3	1
SKIN	LCE6A →	+0.530	+6.022	<.001	.001	3	1
BLOOD_Lymphoma	CLCN1 →	+0.023	+4.058	.004	.009	2	1
BLOOD_Lymphoma	PPIAL4G →	+0.075	+4.312	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

SLC25A21 survival (RNA) · tumor vs normal (RNA) · all SLC25A21 data types