SLC25A1P5

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC25A1P5 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SLC25A1P5 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher SLC25A1P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A1P5 expression acts as an unfavorable survival marker, although some lineages such as PAAD and ESCA show a favorable association.

MESO, PAAD, and KIRC are the cancer types where SLC25A1P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSQuartileAll0.1990.475<.00151view →
PAADOSMedianAll0.6050.294<.00141view →
KIRCDFSQuartileAll0.4990.703.00735view →
LIHCDFSQuartileAll0.3960.595<.00132view →
LGGDFSTertileAll0.6610.815<.00130view →
READDFSMedianAll0.3750.758<.00127view →
KICHDFSQuartileAll0.6601.000.00625view →
OVOSQuartileIII,IV0.6270.743.00324view →
LUSCOSTertileII,III,IV0.3030.616.01818view →
ACCDFSTertileAll0.5280.768.00612view →
ESCADFSTertileII,III,IV0.5470.385.0139view →
UVMDFSTertileIII,IV0.3500.745.0088view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SLC25A1P5–MESO (DFS)

Kaplan–Meier survival curve for SLC25A1P5 RNA-high vs -low samples in MESO.

Open the MESO breakdown →

Exploration