Across TCGA pan-cancer cohorts, SLC25A1P4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SLC25A1P4’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where SLC25A1P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC25A1P4 is over-expressed in tumor.
UCEC, HNSC, and LUSC are the cancer types where SLC25A1P4 tumor–normal differential expression is most reproducible.