SLC25A19

Across TCGA pan-cancer cohorts, SLC25A19 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SLC25A19 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SLC25A19 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A19 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

PDAC, HNSC, and OV are the cancer types where SLC25A19 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.301	0.566	.001	25	view →
HNSC	OS	Median	II,III,IV	0.817	0.614	.006	21	view →
OV	DFS	Tertile	All	0.922	0.442	.015	20	view →
LSCC	OS	Median	II,III,IV	0.887	0.664	.016	19	view →
CCRCC	DFS	Median	II,III,IV	0.473	0.744	.017	18	view →
LUAD	OS	Quartile	III,IV	0.618	0.993	.040	3	view →
UCEC	DFS	Tertile	All	0.818	0.955	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SLC25A19–PDAC (DFS)

Open the PDAC breakdown →