SLC25A18

Across TCGA patient cohorts, SLC25A18 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,136 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SLC25A18-associated GO terms across cancer lineages are Protein import into peroxisome membrane, Peroxisomal transport, and Pyruvate metabolic process. Each is linked with SLC25A18 in more than 20 cancer types. Because this analysis shows association rather than direction, both SLC25A18-to-partner and partner-to-SLC25A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein import into peroxisome membrane grouped by SLC25A18-low versus SLC25A18-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A18→partner) and Y-score (partner→SLC25A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Protein import into peroxisome membrane →	+0.054	+0.567	<.001	.006	2	21
STAD	Peroxisomal transport →	+0.052	+0.152	<.001	<.001	3	17
STAD	Pyruvate metabolic process →	+0.049	+0.146	<.001	<.001	3	17
STAD	Protein targeting to peroxisome →	+0.057	+0.161	<.001	<.001	3	16
ACC	Protein import into peroxisome matrix →	+0.054	+0.561	<.001	<.001	3	15
STAD	Protein targeting to membrane →	+0.049	+0.159	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,136 associations by consensus.

Protein import into peroxisome membrane by SLC25A18 expression — UCS

Explore this box plot interactively →