SLC25A18

Across TCGA cell cohorts, SLC25A18 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,996 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC25A18-associated GO terms across cancer lineages are Oxidative phosphorylation, Proton transmembrane transport, and Protein localization to vacuole. Each is linked with SLC25A18 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC25A18-to-partner and partner-to-SLC25A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxidative phosphorylation grouped by SLC25A18-low versus SLC25A18-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A18→partner) and Y-score (partner→SLC25A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Oxidative phosphorylation →	+0.080	+1.028	<.001	<.001	3	10
URINARY_TRACT	Proton transmembrane transport →	+0.046	+0.179	.005	.001	2	10
BLOOD_Leukemia	Protein localization to vacuole →	+0.046	+0.082	<.001	.005	3	9
CNS	Membrane protein proteolysis →	+0.094	+0.795	<.001	.002	3	8
LUNG_NSCLC_LUAD	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.063	+0.390	.002	.008	3	8
LARGE_INTESTINE	Process utilizing autophagic mechanism →	+0.049	+0.120	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,996 associations by consensus.

Oxidative phosphorylation by SLC25A18 expression — CNS

Explore this box plot interactively →