SLC25A18

Across TCGA cell cohorts, SLC25A18 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A18-associated genes across cancer lineages are OR13C3, VSX2, and C20orf85. Each is linked with SLC25A18 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A18-to-partner and partner-to-SLC25A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C3 grouped by SLC25A18-low versus SLC25A18-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A18→partner) and Y-score (partner→SLC25A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR13C3 →	+0.022	+4.887	<.001	.009	3	1
BLOOD_Leukemia	VSX2 →	+0.035	+4.258	<.001	.002	3	1
BLOOD_Leukemia	C20orf85 →	+0.029	+4.384	<.001	.006	3	1
BLOOD_Leukemia	IL22 →	+0.030	+4.984	<.001	.002	3	1
BLOOD_Leukemia	CST5 →	+0.536	+3.551	<.001	.009	3	1
BLOOD_Leukemia	TSSK1B →	+0.006	+5.289	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR13C3 by SLC25A18 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →