SLC25A16

Across TCGA patient cohorts, SLC25A16 protein abundance is significantly associated with the RNA expression of many other genes, with 6,251 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLC25A16-associated genes across cancer lineages are AKT3, GBP1, and AVPR2. Each is linked with SLC25A16 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC25A16-to-partner and partner-to-SLC25A16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A16 versus AKT3 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A16→partner) and Y-score (partner→SLC25A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKT3 →	-0.641	-0.210	<.001	<.001	3	3
BRCA	GBP1 →	-1.207	-0.508	<.001	<.001	3	3
UCEC	AVPR2 →	-0.460	-0.397	.001	<.001	3	3
PDAC	IER5 →	-0.550	-0.407	.004	.001	3	3
LUAD	AQP3 →	+1.477	+0.388	<.001	<.001	3	3
GBM	E2F7 →	-0.781	-0.238	.008	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,251 associations by consensus.

SLC25A16 vs AKT3 — LSCC

Explore this scatter interactively →