SLC25A16

Across TCGA patient cohorts, SLC25A16 mutation is significantly associated with the RNA expression of many other genes, with 2,080 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A16-associated genes across cancer lineages are RNA5SP407, RPL12P45, and OR8G2P. Each is linked with SLC25A16 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A16-to-partner and partner-to-SLC25A16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP407 grouped by SLC25A16-low versus SLC25A16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A16→partner) and Y-score (partner→SLC25A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP407 →	+0.263	+2.977	<.001	.009	3	2
CESC	RPL12P45 →	+0.173	+4.503	<.001	.005	3	2
BLCA	OR8G2P →	+0.128	+5.411	<.001	.005	3	2
UCEC	BNIP3P41 →	+0.017	+4.893	<.001	.001	3	2
UCEC	LIN7C →	+0.663	+3.330	.003	.005	3	1
UCEC	PGAP2 →	+0.477	+3.337	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,080 associations by consensus.

RNA5SP407 by SLC25A16 expression — UCEC

Explore this box plot interactively →