Across TCGA pan-cancer cohorts, SLC25A15P5 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SLC25A15P5’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC25A15P5 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC25A15P5 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.
KIRC, BRCA, and LUSC are the cancer types where SLC25A15P5 tumor–normal differential expression is most reproducible.