SLC25A14

Across TCGA pan-cancer cohorts, SLC25A14 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC25A14 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC25A14 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A14 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

UCEC, LSCC, and GBM are the cancer types where SLC25A14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.350	1.000	.006	12	view →
LSCC	DFS	Median	II,III,IV	0.750	1.000	.022	8	view →
GBM	DFS	Quartile	All	0.832	0.686	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC25A14–UCEC (DFS)

Open the UCEC breakdown →