SLC25A14

Across TCGA patient cohorts, SLC25A14 mutation is significantly associated with the RNA expression of many other genes, with 4,436 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A14-associated genes across cancer lineages are CRYBB2P1, GINS1, and CHEK1. Each is linked with SLC25A14 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A14-to-partner and partner-to-SLC25A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB2P1 grouped by SLC25A14-low versus SLC25A14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A14→partner) and Y-score (partner→SLC25A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CRYBB2P1 →	+0.421	+2.592	.001	<.001	3	3
UCEC	GINS1 →	+0.607	+1.606	.002	.006	3	3
UCEC	CHEK1 →	+0.802	+2.223	<.001	<.001	3	3
UCEC	BUB1B →	+0.918	+2.595	<.001	<.001	3	3
UCEC	PEX13 →	+0.426	+1.895	.001	.001	3	3
UCEC	CIP2A →	+0.741	+2.584	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,436 associations by consensus.

CRYBB2P1 by SLC25A14 expression — UCEC

Explore this box plot interactively →