SLC25A14

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A14 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A14-associated genes across cancer lineages are ZP2 and CENPVL3. Each is linked with SLC25A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A14-to-partner and partner-to-SLC25A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZP2 grouped by SLC25A14-low versus SLC25A14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A14→partner) and Y-score (partner→SLC25A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEZP2 →+0.130+3.678.003.00931
LARGE_INTESTINECENPVL3 →+0.329+3.920<.001.00531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ZP2 by SLC25A14 expression — LARGE_INTESTINE

Box plot of ZP2 in SLC25A14-low vs SLC25A14-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration