SLC25A13

Across TCGA cell cohorts, SLC25A13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,376 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC25A13-associated GO terms across cancer lineages are Malate-aspartate shuttle, Positive regulation of isotype switching to IgG isotypes, and Lagging strand elongation. Each is linked with SLC25A13 in more than 14 cancer types. Because this analysis shows association rather than direction, both SLC25A13-to-partner and partner-to-SLC25A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Malate-aspartate shuttle grouped by SLC25A13-low versus SLC25A13-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A13→partner) and Y-score (partner→SLC25A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Malate-aspartate shuttle →	+0.148	+1.146	<.001	<.001	3	15
SKIN	Positive regulation of isotype switching to IgG isotypes →	+0.135	+1.403	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Lagging strand elongation →	+0.151	+1.049	.009	.001	3	10
SOFT_TISSUE	mRNA 3'-end processing →	+0.084	+1.111	.001	.001	3	10
SOFT_TISSUE	Replication fork processing →	+0.118	+1.493	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of viral genome replication →	+0.067	+0.800	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,376 associations by consensus.

Malate-aspartate shuttle by SLC25A13 expression — LUNG_SCLC

Explore this box plot interactively →