SLC25A12

Across TCGA patient cohorts, SLC25A12 mutation is significantly associated with the RNA expression of many other genes, with 1,631 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A12-associated genes across cancer lineages are LSM3, PARP2, and NOL12. Each is linked with SLC25A12 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A12-to-partner and partner-to-SLC25A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM3 grouped by SLC25A12-low versus SLC25A12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A12→partner) and Y-score (partner→SLC25A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM3 →	+0.412	+1.716	.004	.004	3	3
UCEC	PARP2 →	+0.377	+1.716	.003	.004	3	3
UCEC	NOL12 →	+0.273	+1.748	.003	.002	3	2
UCEC	H2AC14 →	+0.770	+3.010	<.001	<.001	3	2
UCEC	OXSM →	+0.299	+2.057	.001	.004	3	2
UCEC	SKA1 →	+0.483	+3.480	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,631 associations by consensus.

LSM3 by SLC25A12 expression — UCEC

Explore this box plot interactively →