SLC25A12

Across TCGA patient cohorts, SLC25A12 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A12-associated genes across cancer lineages are eIF4E, MEK1, and PCNA. Each is linked with SLC25A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A12-to-partner and partner-to-SLC25A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC25A12-low versus SLC25A12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A12→partner) and Y-score (partner→SLC25A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.200	+2.906	.009	.001	3	2
UCEC	MEK1 →	+0.338	+2.906	.011	.001	3	2
UCEC	PCNA →	+0.172	+1.502	.030	.030	3	2
UCEC	Smad1 →	+0.139	+3.169	.016	.018	3	2
UCEC	TFRC →	+0.581	+2.700	.002	.006	3	2
UCEC	14-3-3_beta →	-0.090	-2.432	.014	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

eIF4E by SLC25A12 expression — UCEC

Explore this box plot interactively →