SLC25A11

Across TCGA patient cohorts, SLC25A11 mutation is significantly associated with the RNA expression of many other genes, with 634 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A11-associated genes across cancer lineages are OAZ1, SLC15A4, and SOCS2-AS1. Each is linked with SLC25A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A11-to-partner and partner-to-SLC25A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OAZ1 grouped by SLC25A11-low versus SLC25A11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A11→partner) and Y-score (partner→SLC25A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OAZ1 →	+0.361	+3.475	.004	.002	3	2
UCEC	SLC15A4 →	+0.467	+2.415	<.001	.003	3	2
UCEC	SOCS2-AS1 →	+0.381	+2.716	.006	.003	3	2
SKCM	MIR7845 →	+0.266	+2.864	<.001	.006	3	2
UCEC	TMEM256-PLSCR3 →	+0.086	+2.533	.001	.001	3	1
UCEC	MIR4804 →	+0.390	+2.648	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 634 associations by consensus.

OAZ1 by SLC25A11 expression — UCEC

Explore this box plot interactively →