SLC25A11

Across TCGA cell cohorts, SLC25A11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,436 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A11-associated GO terms across cancer lineages are Alpha-ketoglutarate transport, Mitochondrial DNA metabolic process, and Beta-arrestin-dependent dopamine receptor signaling pathway. Each is linked with SLC25A11 in more than 14 cancer types. Because this analysis shows association rather than direction, both SLC25A11-to-partner and partner-to-SLC25A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alpha-ketoglutarate transport grouped by SLC25A11-low versus SLC25A11-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A11→partner) and Y-score (partner→SLC25A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Alpha-ketoglutarate transport →	+0.352	+0.740	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Mitochondrial DNA metabolic process →	+0.104	+1.040	.002	<.001	3	14
URINARY_TRACT	Beta-arrestin-dependent dopamine receptor signaling pathway →	+0.163	+0.783	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Transcription initiation at RNA polymerase II promoter →	+0.073	+0.677	<.001	.009	3	13
CNS	Regulation of establishment of protein localization to chromosome →	+0.099	+0.543	<.001	.002	2	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated DNA replication →	+0.167	+0.924	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,436 associations by consensus.

Alpha-ketoglutarate transport by SLC25A11 expression — BREAST

Explore this box plot interactively →