SLC25A11

Across TCGA cell cohorts, SLC25A11 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC25A11-associated genes across cancer lineages are IL21, OR2AJ1, and CCR8. Each is linked with SLC25A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A11-to-partner and partner-to-SLC25A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL21 grouped by SLC25A11-low versus SLC25A11-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A11→partner) and Y-score (partner→SLC25A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IL21 →	+0.143	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR2AJ1 →	+0.013	+5.369	<.001	.004	3	1
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

IL21 by SLC25A11 expression — SOFT_TISSUE

Explore this box plot interactively →