SLC25A1

Across TCGA patient cohorts, SLC25A1 mutation is significantly associated with the RNA expression of many other genes, with 1,896 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A1-associated genes across cancer lineages are RNA5SP136, RNU6-1124P, and RNU6-320P. Each is linked with SLC25A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A1-to-partner and partner-to-SLC25A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP136 grouped by SLC25A1-low versus SLC25A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A1→partner) and Y-score (partner→SLC25A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP136 →	+0.220	+2.714	.002	.005	3	2
STAD	RNU6-1124P →	+0.277	+6.070	<.001	.002	3	1
STAD	RNU6-320P →	+0.472	+5.366	<.001	.005	3	1
STAD	MIR3675 →	+0.368	+5.798	<.001	.003	3	1
UCEC	PPIL2 →	+0.387	+2.818	.006	.001	3	1
UCEC	CRYBB2P1 →	+0.493	+3.467	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,896 associations by consensus.

RNA5SP136 by SLC25A1 expression — UCEC

Explore this box plot interactively →