SLC25A1

Across TCGA cell cohorts, SLC25A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,249 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC25A1-associated GO terms across cancer lineages are ERBB3 signaling pathway, ERBB2-ERBB3 signaling pathway, and Interleukin-34-mediated signaling pathway. Each is linked with SLC25A1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SLC25A1-to-partner and partner-to-SLC25A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERBB3 signaling pathway grouped by SLC25A1-low versus SLC25A1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A1→partner) and Y-score (partner→SLC25A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ERBB3 signaling pathway →	+0.247	+0.766	<.001	<.001	3	15
LIVER	ERBB2-ERBB3 signaling pathway →	+0.247	+0.766	<.001	<.001	3	15
KIDNEY	Interleukin-34-mediated signaling pathway →	+0.246	+0.811	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.161	+0.757	<.001	.003	3	14
LUNG_NSCLC_LUAD	Terpenoid biosynthetic process →	+0.127	+0.860	<.001	<.001	3	14
URINARY_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.135	+1.728	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,249 associations by consensus.

ERBB3 signaling pathway by SLC25A1 expression — LIVER

Explore this box plot interactively →